Upregulation of Peroxiredoxin-2 in Well-Differentiated Pancreatic Neuroendocrine Tumors and Its Utility as a Biomarker for Predicting the Response to Everolimus

• Główni autorzy: Eui Joo Kim (Autor), Yoon Jae Kim (Autor), Hye In Lee (Autor), Seok-Hoo Jeong (Autor), Hyo Jung Nam (Autor), Jae Hee Cho (Autor)
• Format: Książka
• Wydane: MDPI AG, 2020-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Pancreatic neuroendocrine neoplasms (pNENs) account for 2-3% of pancreatic malignancies. Peroxiredoxins (Prdxs), which are major cellular antioxidants, are involved in multiple oncogenic signaling pathways. We investigated the role of peroxiredoxin-2 in QGP-1 human pNEN cell line and patient-derived...