Pulmonary Pharmacokinetics of Antibody and Antibody Fragments Following Systemic and Local Administration in Mice

• मुख्य लेखकों: Prabhas Jagdale (लेखक), Ashwni Verma (लेखक), Dhaval K. Shah (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

<b>Objective:</b> This study aimed to investigate the effect of molecular size on the pulmonary pharmacokinetics (PK) of proteins following systemic and local administration in wild-type mice. <b>Methods:</b> A non-cross-reactive antibody trastuzumab, and F(ab')2, Fab, a...