Gold-containing compound BDG-I inhibits the growth of A549 lung cancer cells through the deregulation of miRNA expression

• Main Authors: Ali Alhoshani (Author), A. Alrashdi (Author), Khaled Alhosaini (Author), Fawaz E. Alanazi (Author), Nehad M. Alajez (Author), Muhammad Altaf (Author), Anvarhusein A. Isab (Author), Hesham M. Korashy (Author)
• Format: Book
• Published: Elsevier, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gold complex bis(diethyldithiocarbamato-gold(I)) bis(diphenylphosphino) methane (BDG-I) is cytotoxic toward different cancer cell lines. We compared the cytotoxic effect of BDG-I with that of cisplatin in the A549 lung cancer cell line. Additionally, we investigated the molecular mechanism underlyin...