Inhibition of Peptidyl Arginine Deiminase-4 Prevents Renal Ischemia-Reperfusion-Induced Remote Lung Injury

• Hauptverfasser: Mingjun Du (Verfasst von), Lei Yang (Verfasst von), Jianmin Gu (Verfasst von), Jiawei Wu (Verfasst von), Yiwen Ma (Verfasst von), Tao Wang (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2020-01-01T00:00:00Z.
• Schlagworte: article
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Ischemia reperfusion (IR) can lead to acute kidney injury and can be complicated by acute lung injury, which is one of the leading causes of acute kidney injury-related death. Peptidyl arginine deiminase-4 (PAD4) is a member of the PAD enzyme family and plays a critical role in inflammatory reaction...