Optimization of Statin-Loaded Delivery Nanoparticles for Treating Chronic Liver Diseases by Targeting Liver Sinusoidal Endothelial Cells

Optimization of Statin-Loaded Delivery Nanoparticles for Treating Chronic Liver Diseases by Targeting Liver Sinusoidal Endothelial Cells

In this study, we developed functionalized polymeric micelles (FPMs) loaded with simvastatin (FPM-Sim) as a drug delivery system to target liver sinusoidal endothelial cells (LSECs) for preserving liver function in chronic liver disease (CLD). Polymeric micelles (PMs) were functionalized by coupling...

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Main Authors: Mar Gil (Author), Lareen Khouri (Author), Imma Raurell (Author), Diana Rafael (Author), Fernanda Andrade (Author), Ibane Abasolo (Author), Simo Schwartz (Author), María Martínez-Gómez (Author), María Teresa Salcedo (Author), Juan Manuel Pericàs (Author), Diana Hide (Author), Mingxing Wei (Author), Norman Metanis (Author), Joan Genescà (Author), María Martell (Author)
Format: Book
Published: MDPI AG, 2023-10-01T00:00:00Z.
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