(Dis)Solving the problem of aberrant protein states

• मुख्य लेखकों: Charlotte M. Fare (लेखक), James Shorter (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2021-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Neurodegenerative diseases and other protein-misfolding disorders represent a longstanding biomedical challenge, and effective therapies remain largely elusive. This failure is due, in part, to the recalcitrant and diverse nature of misfolded protein conformers. Recent work has uncovered that many a...