Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production

• Main Authors: Mohamed El-Sherbiny (Author), Hoda Atef (Author), Mohamed Ahmed Eladl (Author), Abdelaty Shawky Mohamed (Author), Mohamed El-Shafey (Author), Howaida S. Ali (Author), Sawsan A. Zaitone (Author), Suliman Y. Alomar (Author), Saeed Awad M. Alqahtani (Author), Sheka Yagub Aloyouni (Author), Mohammed A. Attia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, the therapeutic importance of the anti-rheumatic drug, leflunomide, has been increased after the involvement of leflunomide in treating other autoimmune diseases and its promising role in retarding human malignancies. Few studies have focused on the safety in human or animals without clear...