AK2 Promotes the Migration and Invasion of Lung Adenocarcinoma by Activating TGF-β/Smad Pathway In vitro and In vivo

• Main Authors: Fangfang Cai (Author), Huangru Xu (Author), Daolong Zha (Author), Xiaoyang Wang (Author), Ping Li (Author), Shihui Yu (Author), Yingying Yao (Author), Xiaoyao Chang (Author), Jia Chen (Author), Yanyan Lu (Author), Zi-Chun Hua (Author), Hongqin Zhuang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adenylate kinase 2 (AK2) is a wide-spread and highly conserved protein kinase whose main function is to catalyze the exchange of nucleotide phosphate groups. In this study, we showed that AK2 regulated tumor cell metastasis in lung adenocarcinoma. Positive expression of AK2 is related to lung adenoc...