IDH1 mutated low grade astrocytoma occurring in MSH2 mutated Lynch syndrome family

• Κύριοι συγγραφείς: Alaa Alkhotani (Συγγραφέας), Ingrid Ambus (Συγγραφέας), Lea Velsher (Συγγραφέας), Corwyn Rowsell (Συγγραφέας), Julia Keith (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2016-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Lynch syndrome (LS) is an autosomal dominant tumour predisposition syndrome caused by a germline mutation in one of the DNA mismatch repair (MMR) genes.Patients with these mutations have an increased risk of brain tumours, the vast majority of which are glioblastomas and medulloblastomas, and their...