New Pyrazolyl Thioureas Active against the <i>Staphylococcus</i> Genus

• Main Authors: Anna Maria Schito (Author), Debora Caviglia (Author), Susanna Penco (Author), Andrea Spallarossa (Author), Elena Cichero (Author), Bruno Tasso (Author), Chiara Brullo (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To meet the urgent need for new antibacterial molecules, a small library of pyrazolyl thioureas (PTUs) was designed, synthesized and tested against difficult-to-treat human pathogens. The prepared derivatives are characterized by a carboxyethyl functionality on C4 and different hydroxyalkyl chains o...