Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• المؤلفون الرئيسيون: Philippe-Henri Secretan (مؤلف), Maxime Annereau (مؤلف), Willy Kini-Matondo (مؤلف), Bastien Prost (مؤلف), Jade Prudhomme (مؤلف), Lina Bournane (مؤلف), Muriel Paul (مؤلف), Najet Yagoubi (مؤلف), Hassane Sadou-Yayé (مؤلف), Bernard Do (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...