Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• Autors principals: Philippe-Henri Secretan (Autor), Maxime Annereau (Autor), Willy Kini-Matondo (Autor), Bastien Prost (Autor), Jade Prudhomme (Autor), Lina Bournane (Autor), Muriel Paul (Autor), Najet Yagoubi (Autor), Hassane Sadou-Yayé (Autor), Bernard Do (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2022-08-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...