Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• Prif Awduron: Philippe-Henri Secretan (Awdur), Maxime Annereau (Awdur), Willy Kini-Matondo (Awdur), Bastien Prost (Awdur), Jade Prudhomme (Awdur), Lina Bournane (Awdur), Muriel Paul (Awdur), Najet Yagoubi (Awdur), Hassane Sadou-Yayé (Awdur), Bernard Do (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2022-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...