Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• Hauptverfasser: Philippe-Henri Secretan (Verfasst von), Maxime Annereau (Verfasst von), Willy Kini-Matondo (Verfasst von), Bastien Prost (Verfasst von), Jade Prudhomme (Verfasst von), Lina Bournane (Verfasst von), Muriel Paul (Verfasst von), Najet Yagoubi (Verfasst von), Hassane Sadou-Yayé (Verfasst von), Bernard Do (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-08-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...