Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• Päätekijät: Philippe-Henri Secretan (Tekijä), Maxime Annereau (Tekijä), Willy Kini-Matondo (Tekijä), Bastien Prost (Tekijä), Jade Prudhomme (Tekijä), Lina Bournane (Tekijä), Muriel Paul (Tekijä), Najet Yagoubi (Tekijä), Hassane Sadou-Yayé (Tekijä), Bernard Do (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...