Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• Autori principali: Philippe-Henri Secretan (Autore), Maxime Annereau (Autore), Willy Kini-Matondo (Autore), Bastien Prost (Autore), Jade Prudhomme (Autore), Lina Bournane (Autore), Muriel Paul (Autore), Najet Yagoubi (Autore), Hassane Sadou-Yayé (Autore), Bernard Do (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...