Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• Главные авторы: Philippe-Henri Secretan (Автор), Maxime Annereau (Автор), Willy Kini-Matondo (Автор), Bastien Prost (Автор), Jade Prudhomme (Автор), Lina Bournane (Автор), Muriel Paul (Автор), Najet Yagoubi (Автор), Hassane Sadou-Yayé (Автор), Bernard Do (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2022-08-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...