Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

• Váldodahkkit: Philippe-Henri Secretan (Dahkki), Maxime Annereau (Dahkki), Willy Kini-Matondo (Dahkki), Bastien Prost (Dahkki), Jade Prudhomme (Dahkki), Lina Bournane (Dahkki), Muriel Paul (Dahkki), Najet Yagoubi (Dahkki), Hassane Sadou-Yayé (Dahkki), Bernard Do (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2022-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID^®. Although knowledge of nirmatrelvir's intrinsic stability may be useful for any potential development of other p...