Chemically Defined <i>Lactobacillus plantarum</i> Cell-Free Metabolites Demonstrate Cytoprotection in HepG2 Cells through Nrf2-Dependent Mechanism

• Main Authors: Raja Rezgui (Author), Ruhi Walia (Author), Jyoti Sharma (Author), Dwinder Sidhu (Author), Khalid Alshagadali (Author), Saumya Ray Chaudhuri (Author), Amir Saeed (Author), Priyankar Dey (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Centering around the concept that metabolites from the gut commensals can exert metabolic health benefits along the gut-liver axis, we tested whether the cell-free global metabolome of probiotic bacteria can exert hepatoprotective benefits against H₂O₂-i...