Analytical and diagnostic performance characteristics of reverse-transcriptase loop-mediated isothermal amplification assays for dengue virus serotypes 1-4: A scoping review to inform potential use in portable molecular diagnostic devices.

Analytical and diagnostic performance characteristics of reverse-transcriptase loop-mediated isothermal amplification assays for dengue virus serotypes 1-4: A scoping review to inform potential use in portable molecular diagnostic devices.

Dengue is a mosquito-borne disease caused by dengue virus (DENV) serotypes 1-4 which affects 100-400 million adults and children each year. Reverse-transcriptase (RT) quantitative polymerase chain reaction (qPCR) assays are the current gold-standard in diagnosis and serotyping of infections, but the...

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Main Authors: Paul Arkell (Author), Dumrong Mairiang (Author), Adisak Songjaeng (Author), Kenny Malpartida-Cardenas (Author), Kerri Hill-Cawthorne (Author), Panisadee Avirutnan (Author), Pantelis Georgiou (Author), Alison Holmes (Author), Jesus Rodriguez-Manzano (Author)
Format: Book
Published: Public Library of Science (PLoS), 2023-01-01T00:00:00Z.
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