Blood Transcriptional Profiling Reveals Immunological Signatures of Distinct States of Infection of Humans with Leishmania infantum.

• Main Authors: Luiz Gustavo Gardinassi (Author), Gustavo Rocha Garcia (Author), Carlos Henrique Nery Costa (Author), Vladimir Costa Silva (Author), Isabel Kinney Ferreira de Miranda Santos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Visceral leishmaniasis (VL) can be lethal if untreated; however, the majority of human infections with the etiological agents are asymptomatic. Using Illumina Bead Chip microarray technology, we investigated the patterns of gene expression in blood of active VL patients, asymptomatic infected indivi...