Diverse Biological Activity of Benzofuroxan/Sterically Hindered Phenols Hybrids

• Main Authors: Elena Chugunova (Author), Elmira Gibadullina (Author), Kirill Matylitsky (Author), Baurat Bazarbayev (Author), Margarita Neganova (Author), Konstantin Volcho (Author), Artem Rogachev (Author), Nurgali Akylbekov (Author), Hoang Bao Tran Nguyen (Author), Alexandra Voloshina (Author), Anna Lyubina (Author), Syumbelya Amerhanova (Author), Victor Syakaev (Author), Alexander Burilov (Author), Nurbol Appazov (Author), Mukhtar Zhanakov (Author), Leah Kuhn (Author), Oleg Sinyashin (Author), Igor Alabugin (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Combining two pharmacophores in a molecule can lead to useful synergistic effects. Herein, we show hybrid systems that combine sterically hindered phenols with dinitrobenzofuroxan fragments exhibit a broad range of biological activities. The modular assembly of such phenol/benzofuroxan hybrids allow...