Pharmacophore modeling and virtual screening for the discovery of new fatty acid amide hydrolase inhibitors

A predictive pharmacophore model has been generated from a series of diverse fatty acid amide hydrolase (FAAH) inhibitors and the optimal pharmacophore model applied in virtual screening. The pharmacophore model was based on a training set of 21 compounds carefully selected from the published litera...

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Bibliographic Details
Main Authors: Dong-sheng Zhao (Author), Hai-yan Wang (Author), Zhi-hui Lian (Author), Da-xiong Han (Author), Xin Jin (Author)
Format: Book
Published: Elsevier, 2011-06-01T00:00:00Z.
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