Pharmacophore modeling and virtual screening for the discovery of new fatty acid amide hydrolase inhibitors

• Váldodahkkit: Dong-sheng Zhao (Dahkki), Hai-yan Wang (Dahkki), Zhi-hui Lian (Dahkki), Da-xiong Han (Dahkki), Xin Jin (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2011-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

A predictive pharmacophore model has been generated from a series of diverse fatty acid amide hydrolase (FAAH) inhibitors and the optimal pharmacophore model applied in virtual screening. The pharmacophore model was based on a training set of 21 compounds carefully selected from the published litera...