Association between arachidonate lipoxygenase 15,c.-292 C > T gene polymorphism and non-cystic fibrosis bronchiectasis in children: a pilot study on the effects on airway lipoxin A4 and disease phenotype

• मुख्य लेखकों: Mahitab Morsy Hussein (लेखक), Eman Mahmoud Fouda (लेखक), Yasmine Shehab (लेखक), Enas Samir Nabih (लेखक), Ahmed Mohamed Osman (लेखक), Sally Raafat Ishak (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2024-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Persistent airway inflammation is a central feature of bronchiectasis. Arachidonate 15-lipoxygenase (ALOX-15) controls production of endogenous lipid mediators, including lipoxins that regulate airway inflammation. Mutations at various positions in ALOX-15 gene can influence airw...