The impact of NRG1 expressions and methylation on multifactorial Hirschsprung disease

• मुख्य लेखकों: Gunadi (लेखक), Alvin Santoso Kalim (लेखक), Marcellus (लेखक), Nova Yuli Prasetyo Budi (लेखक), Kristy Iskandar (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Hirschsprung disease (HSCR) is a complex genetic disorder characterized by the lack of ganglion cells in the intestines. A current study showed that the NRG1 rare variant frequency in Indonesian patients with HSCR is only 0.9%. Here, we investigated the impact of NRG1 expressions...