Concentration-Dependent Activity of Pazufloxacin against <i>Pseudomonas aeruginosa</i>: An In Vivo Pharmacokinetic/Pharmacodynamic Study

• Ngā kaituhi matua: Yasuhiro Umezaki (Author), Kazuaki Matsumoto (Author), Kazuro Ikawa (Author), Yuta Yokoyama (Author), Yuki Enoki (Author), Akari Shigemi (Author), Erika Watanabe (Author), Koyo Nakamura (Author), Keiichiro Ueno (Author), Hideyuki Terazono (Author), Norifumi Morikawa (Author), Yasuo Takeda (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2022-07-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

The bacterium <i>Pseudomonas aeruginosa</i> is known to be associated with nosocomial infections around the world. Pazufloxacin, a potent DNA gyrase inhibitor, is known to be an effective drug candidate. However, it has not been clarified whether the pharmacokinetic (PK)/pharmacodynamic...