TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway

• Main Authors: Yun Zhang (Author), Hong-Mei Tang (Author), Chun-Feng Liu (Author), Xie-Fang Yuan (Author), Xiao-Yun Wang (Author), Ning Ma (Author), Guo-Feng Xu (Author), Song-Ping Wang (Author), Jun Deng (Author), Xing Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Higher concentrations of reactive oxygen species (ROS) have been associated with epithelial cell damage, cell shedding, and airway hyperresponsiveness. Previous studies have indicated that transforming growth factor-beta (TGF-β) mediates ROS production and NADPH oxidase (NOX) activity. In our previo...