Angiotensin II Type I Receptor Antagonism Attenuates Nicotine-Induced Cardiac Remodeling, Dysfunction, and Aggravation of Myocardial Ischemia-Reperfusion Injury in Rats

• Príomhchruthaitheoirí: Anand Ramalingam (Údar), Siti Balkis Budin (Údar), Norsyahida Mohd. Fauzi (Údar), Rebecca H. Ritchie (Údar), Satirah Zainalabidin (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Increased exposure to nicotine contributes to the development of cardiac dysfunction by promoting oxidative stress, fibrosis, and inflammation. These deleterious events altogether render cardiac myocytes more susceptible to acute cardiac insults such as ischemia-reperfusion (I/R) injury. This study...