PEG-Modified <i>tert</i>-Octylcalix[8]arenes as Drug Delivery Nanocarriers of Silibinin

• Main Authors: Desislava Budurova (Author), Denitsa Momekova (Author), Georgi Momekov (Author), Pavletta Shestakova (Author), Hristo Penchev (Author), Stanislav Rangelov (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The hepatoprotective properties of silibinin, as well its therapeutic potential as an anticancer and chemo-preventive agent, have failed to progress towards clinical development and commercialization due to this material's unfavorable pharmacokinetics and physicochemical properties, low aqueous...