Inhibitory Action of Antidiabetic Drugs on the Free Radical Production by the Rod Outer Segment Ectopic Aerobic Metabolism

• Main Authors: Silvia Ravera (Author), Federico Caicci (Author), Paolo Degan (Author), Davide Maggi (Author), Lucia Manni (Author), Alessandra Puddu (Author), Massimo Nicolò (Author), Carlo E. Traverso (Author), Isabella Panfoli (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rod outer segments (OS) express the F_oF₁-ATP synthase and the respiratory chain, conducting an ectopic aerobic metabolism that produces free radicals in vitro. Diabetic retinopathy, a leading cause of vision loss, is associated with oxidative stress in t...