Interaction between DNA, Albumin and Apo-Transferrin and Iridium(III) Complexes with Phosphines Derived from Fluoroquinolones as a Potent Anticancer Drug

A group of cytotoxic half-sandwich iridium(III) complexes with aminomethyl(diphenyl)phosphine derived from fluoroquinolone antibiotics exhibit the ability to (i) accumulate in the nucleus, (ii) induce apoptosis, (iii) activate caspase-3/7 activity, (iv) induce the changes in cell cycle leading to G2...

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Main Authors: Sandra Amanda Kozieł (Author), Monika Katarzyna Lesiów (Author), Daria Wojtala (Author), Edyta Dyguda-Kazimierowicz (Author), Dariusz Bieńko (Author), Urszula Katarzyna Komarnicka (Author)
Format: Book
Published: MDPI AG, 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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