In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against <i>Candida auris</i>

• Auteurs principaux: Unai Caballero (Auteur), Elena Eraso (Auteur), Javier Pemán (Auteur), Guillermo Quindós (Auteur), Valvanera Vozmediano (Auteur), Stephan Schmidt (Auteur), Nerea Jauregizar (Auteur)
• Format: Livre
• Publié: MDPI AG, 2021-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The aims of this study were to characterize the antifungal activity of amphotericin B against <i>Candida auris</i> in a static in vitro system and to evaluate different dosing schedules and MIC scenarios by means of semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) modelling and s...