In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against <i>Candida auris</i>

• Main Authors: Unai Caballero (Author), Elena Eraso (Author), Javier Pemán (Author), Guillermo Quindós (Author), Valvanera Vozmediano (Author), Stephan Schmidt (Author), Nerea Jauregizar (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aims of this study were to characterize the antifungal activity of amphotericin B against <i>Candida auris</i> in a static in vitro system and to evaluate different dosing schedules and MIC scenarios by means of semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) modelling and s...