Biphasic Effect of TNF-α on the Survival and Endocrine Function of Human Ovarian Granulosa Cells

• Main Authors: Haiyan Liang (Author), Dongkui Xu (Author), Xianhong Tong (Author), Bin Ling (Author), Wenhui Wang (Author), Dingqing Feng (Author), Jing Liang (Author)
• Format: Book
• Published: IMR Press, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: TNF-α has a wide range of functions in processes within the ovaries, including follicular development, ovarian hormones synthesis, ovulation, granulosa cell necroptosis, and follicular atresia. Innate immune response in the ovaries is the main source of TNF-α. The purpose of this study i...