Chiral Derivatives of Xanthones: Investigation of the Effect of Enantioselectivity on Inhibition of Cyclooxygenases (COX-1 and COX-2) and Binding Interaction with Human Serum Albumin

Chiral Derivatives of Xanthones: Investigation of the Effect of Enantioselectivity on Inhibition of Cyclooxygenases (COX-1 and COX-2) and Binding Interaction with Human Serum Albumin

Searching of new enantiomerically pure chiral derivatives of xanthones (CDXs) with potential pharmacological properties, particularly those with anti-inflammatory activity, has remained an area of interest of our group. Herein, we describe in silico studies and in vitro inhibitory assays of cyclooxy...

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Main Authors: Carla Fernandes (Author), Andreia Palmeira (Author), Inês I. Ramos (Author), Carlos Carneiro (Author), Carlos Afonso (Author), Maria Elizabeth Tiritan (Author), Honorina Cidade (Author), Paula C.A.G. Pinto (Author), M. Lúcia M.F.S. Saraiva (Author), Salette Reis (Author), Madalena M.M. Pinto (Author)
Format: Book
Published: MDPI AG, 2017-05-01T00:00:00Z.
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