Development and validation of stability-indicating RP-HPLC method for the simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form

• Main Authors: Bhaskar Musmade (Author), Prashant Sanatan (Author), Surbhi Lokhande (Author), Shrikant Kulkarni (Author), Shrinivas Bhope (Author), Sriram Padmanabhan (Author), Amol Pachpinde (Author), Kishan Lohar (Author)
• Format: Book
• Published: SpringerOpen, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background A simple, robust, precise, and an accurate HPLC method was established for simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from a nasal spray dosage form. The effective separation was obtained by injecting 10 μl of sample and standard solutions on...