A brief history of crystalloids: the origin of the controversy

• Main Authors: Jaime Fernández-Sarmiento (Author), Carolina Casas-Certain (Author), Sarah Ferro-Jackaman (Author), Fabian H. Solano-Vargas (Author), Jesús Ángel Domínguez-Rojas (Author), Francisco Javier Pilar-Orive (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fluid resuscitation with crystalloids has been used in humans for more than 100 years. In patients with trauma, sepsis or shock of any etiology, they can help modify the clinical course of the illness. However, these solutions are medications which are not side-effect free. Recently, they have been...