Targeted therapies for myeloproliferative neoplasms

Abstract The discovery of JAK2V617F and the demonstration that BCR-ABL-negative myeloproliferative neoplasms (MPNs) are driven by abnormal JAK2 activation have led to advances in diagnostic algorithms, prognosis and ultimately also treatment strategies. The JAK 1/2 inhibitor ruxolitinib was a pivota...

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Bibliographic Details
Main Authors: Bing Li (Author), Raajit K. Rampal (Author), Zhijian Xiao (Author)
Format: Book
Published: BMC, 2019-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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