Pharmacological and Genetic Inhibition of HDAC4 Alleviates Renal Injury and Fibrosis in Mice

• Príomhchruthaitheoirí: Fengchen Shen (Údar), Xiying Hou (Údar), Tingting Li (Údar), Jianjun Yu (Údar), Huizhen Chen (Údar), Na Liu (Údar), Andong Qiu (Údar), Shougang Zhuang (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Histone deacetylase 4 (HDAC4) has been shown to be involved in cell proliferation, differentiation, and migration and is associated with a variety of cancers. However, the role of HDAC4 in renal fibrogenesis and its mechanisms are unclear. We assessed the role of HDAC4 and possible mechanisms of fib...