Identification of the Schistosoma mansoni TNF-alpha receptor gene and the effect of human TNF-alpha on the parasite gene expression profile.

• Main Authors: Katia C Oliveira (Author), Mariana L P Carvalho (Author), Thiago M Venancio (Author), Patricia A Miyasato (Author), Toshie Kawano (Author), Ricardo DeMarco (Author), Sergio Verjovski-Almeida (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Schistosoma mansoni is the major causative agent of schistosomiasis. The parasite takes advantage of host signals to complete its development in the human body. Tumor necrosis factor-alpha (TNF-alpha) is a human cytokine involved in skin inflammatory responses, and although its effect on...