Contribution of Molecular Structure to Self-Assembling and Biological Properties of Bifunctional Lipid-Like 4-(N-Alkylpyridinium)-1,4-Dihydropyridines

• Main Authors: Martins Rucins (Author), Pavels Dimitrijevs (Author), Klavs Pajuste (Author), Oksana Petrichenko (Author), Ludmila Jackevica (Author), Anita Gulbe (Author), Signe Kibilda (Author), Krisjanis Smits (Author), Mara Plotniece (Author), Dace Tirzite (Author), Karlis Pajuste (Author), Arkadij Sobolev (Author), Janis Liepins (Author), Ilona Domracheva (Author), Aiva Plotniece (Author)
• Format: Book
• Published: MDPI AG, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The design of nanoparticle delivery materials possessing biological activities is an attractive strategy for the development of various therapies. In this study, 11 cationic amphiphilic 4-(N-alkylpyridinium)-1,4-dihydropyridine (1,4-DHP) derivatives differing in alkyl chain length and propargyl moie...