The MET oncogene as a therapeutical target in cancer invasive growth

• Główni autorzy: Paolo eLuraghi (Autor), Florian eSchelter (Autor), Achim eKrüger (Autor), Carla eBoccaccio (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2012-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The MET proto-oncogene, encoding the tyrosine kinase receptor for Hepatocyte Growth Factor (HGF) regulates invasive growth, a genetic program that associates control of cell proliferation with invasion of the extracellular matrix and protection from apoptosis. Physiologically, invasive growth takes...