In Vitro Selection of Cell-Internalizing DNA Aptamers in a Model System of Inflammatory Kidney Disease

• Main Authors: Glory Ranches (Author), Melanie Lukasser (Author), Herbert Schramek (Author), Andreas Ploner (Author), Taras Stasyk (Author), Gert Mayer (Author), Günter Mayer (Author), Alexander Hüttenhofer (Author)
• Format: Book
• Published: Elsevier, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic kidney disease (CKD) is a progressive pathological condition marked by a gradual loss of kidney function. Treatment of CKD is most effective when diagnosed at an early stage and patients are still asymptomatic. However, current diagnostic biomarkers (e.g., serum creatinine and urine albumin)...