Dengue virus infection induces selective expansion of Vγ4 and Vγ6TCR γδ T cells in the small intestine and a cytokine storm driving vascular leakage in mice.

• Main Authors: Takeshi Kurosu (Author), Daisuke Okuzaki (Author), Yusuke Sakai (Author), Mohamad Al Kadi (Author), Supranee Phanthanawiboon (Author), Yasusi Ami (Author), Masayuki Shimojima (Author), Tomoki Yoshikawa (Author), Shuetsu Fukushi (Author), Noriyo Nagata (Author), Tadaki Suzuki (Author), Daisuke Kamimura (Author), Masaaki Murakami (Author), Hideki Ebihara (Author), Masayuki Saijo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue is a major health problem in tropical and subtropical regions. Some patients develop a severe form of dengue, called dengue hemorrhagic fever, which can be fatal. Severe dengue is associated with a transient increase in vascular permeability. A cytokine storm is thought to be the cause of the...