Single Turnover of Transient of Reactants Supports a Complex Interplay of Conformational States in the Mode of Action of <i>Mycobacterium tuberculosis</i> Enoyl Reductase

The enoyl reductase from <i>Mycobacterium tuberculosis</i> (<i>Mt</i>InhA) was shown to be a major target for isoniazid, the most prescribed first-line anti-tuberculosis agent. The <i>Mt</i>InhA (EC 1.3.1.9) protein catalyzes the hydride transfer from the 4<i&g...

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Main Authors: Leonardo Kras Borges Martinelli (Author), Mariane Rotta (Author), Cristiano Valim Bizarro (Author), Pablo Machado (Author), Luiz Augusto Basso (Author)
Format: Book
Published: MDPI AG, 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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