Protein C Pathway in Paediatric and Neonatal Sepsis

• Main Authors: Hassan Eliwan (Author), Murwan Omer (Author), Ellen McKenna (Author), Lynne A. Kelly (Author), Beatrice Nolan (Author), Irene Regan (Author), Eleanor J. Molloy (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein C plays a major role in the physiological regulation of coagulation pathways through inactivation of factor Va, factor VIIIa, and plasminogen activator inhibitor. Protein C is involved in the control of inflammation during sepsis, by inhibiting release of pro-inflammatory cytokines, thereby...