Evaluation of the neuroprotective efficacy of the gramine derivative ITH12657 against NMDA-induced excitotoxicity in the rat retina

Evaluation of the neuroprotective efficacy of the gramine derivative ITH12657 against NMDA-induced excitotoxicity in the rat retina

PurposeThe aim of this study was to investigate, the neuroprotective effects of a new Gramine derivative named: ITH12657, in a model of retinal excitotoxicity induced by intravitreal injection of NMDA.MethodsAdult Sprague Dawley rats received an intravitreal injection of 100 mM NMDA in their left ey...

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Main Authors: Johnny Di Pierdomenico (Author), Alejandro Gallego-Ortega (Author), María Norte-Muñoz (Author), Beatriz Vidal-Villegas (Author), Isaac Bravo (Author), María Boluda-Ruiz (Author), Jose Manuel Bernal-Garro (Author), Iván Fernandez-Bueno (Author), Jose Carlos Pastor-Jimeno (Author), María Paz Villegas-Pérez (Author), Marcelino Avilés-Trigueros (Author), Cristobal de los Ríos (Author), Manuel Vidal-Sanz (Author)
Format: Book
Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
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