Aberrant Expression of Histamine-independent Pruritogenic Mediators in Keratinocytes may be Involved in the Pathogenesis of Prurigo Nodularis

• Hoofdauteurs: Weilong Zhong (Auteur), Xia Wu (Auteur), Wei Zhang (Auteur), Jie Zhang (Auteur), Xiaofan Chen (Auteur), Shihong Chen (Auteur), Haiyan Huang (Auteur), Yong Yang (Auteur), Bo Yu (Auteur), Xia Dou (Auteur)
• Formaat: Boek
• Gepubliceerd in: Medical Journals Sweden, 2019-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in chronic itch and inflammation. This study investiga...