Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer

• Päätekijät: Zhaohui Yang (Tekijä), Yu-Ching Peng (Tekijä), Anuradha Gopalan (Tekijä), Dong Gao (Tekijä), Yu Chen (Tekijä), Alexandra L. Joyner (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: The Company of Biologists, 2017-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

It is widely appreciated that reactive stroma or carcinoma-associated fibroblasts can influence epithelial tumor progression. In prostate cancer (PCa), the second most common male malignancy worldwide, the amount of reactive stroma is variable and has predictive value for tumor recurrence. By analyz...