Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept

• Main Authors: Francesca Pistollato (Author), Emilio Mendoza de Gyves (Author), Donatella Carpi (Author), Stephanie K. Bopp (Author), Carolina Nunes (Author), Andrew Worth (Author), Anna Bal-Price (Author)
• Format: Book
• Published: BMC, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background In light of the vulnerability of the developing brain, mixture risk assessment (MRA) for the evaluation of developmental neurotoxicity (DNT) should be implemented, since infants and children are co-exposed to more than one chemical at a time. One possible approach to tackle MRA c...