Protective Effect of Pomegranate on Oxidative Stress and Inflammatory Response Induced by 5-Fluorouracil in Human Keratinocytes

• Main Authors: Shara Francesca Rapa (Author), Giorgia Magliocca (Author), Giacomo Pepe (Author), Giuseppina Amodio (Author), Giuseppina Autore (Author), Pietro Campiglia (Author), Stefania Marzocco (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

5-Fluorouracil (5-FU) is a pyrimidine analogue used as an antineoplastic agent to treat multiple solid tumors. Despite its use and efficacy, it also has important side effects in healthy cells, including skin reactions, related to its pro-oxidant and pro-inflammatory potential. Although there are nu...